I traded my 2016 LR4 for a 2020 Defender 110 X. I have 3500 miles on it and done a few overlanding/camping trips and I can give my fair assessment of the two. I'll start with the rear cargo room which I miss in the LR4. That extra foot or so in depth is a lot when you pack for two and a couple of dogs. I have to say the clearsight mirror in the Defender is such a great feature when your visibility is limited.
Engine - I had the SCV6 LR4 and with gear, GF, kids and dogs on a 500 plus mile trip I would avg 17 to 18mpg. You really had to wind up the SCV6 for the power to kick in so merging onto the highway can be hit or miss. The inline 6 turbocharged/supercharged mild hybrid Defender you step on it and there is a half of second delay and then it takes off! It takes a while to get used to this coming from a V8 or SCV6. Driving up mountain passes and using the passing lane I put it into sport and this is where the engine really shines. Mpg is around 20 fully loaded so a big bonus in that respect.
On road - The Defender is hands down the winner that regard. Smoother and more refined and on the winding bits there is less understeer than in the LR4. I feel more comfortable in pushing the Defender in a corner. Less body roll which is probably due to the use of the all aluminum body. The turning radius however is pathetic and nearly embarrassing. The LR4 is much more maneuverable so driving in town with the Defender can be a pain. Lucky for me my daily driver is a BMWi3.
Off-road - I'll defer to others who do more technical rock crawling or trails. I'm limited with the all-seasons but from my experience so far the Defender's TR2 is a hands down winner and because of it I've been able to go off the beaten path with more confidence than my LR4 with off road tires. (my LR4 did not have the HD package).
Interior - This is subjective so take it as a grain of salt. I've done 7 hour plus driving in both and I will give the edge to the Defender but the LR4 is not far behind...at least that what my behind says

The LR4 interior is more upscale and if there was a Apple carplay feature you may want to keep your LR4. The utilitarian interior of the Defender has grown on me and it is a conversation piece for passengers not familiar with the Defender. Not sure with the 130 but you can lay the rear seats flat in the 110. I've slept 6 nights in the Defender and many night in the LR4 and they both work well. I added an extra air mattress for better comfort. Oh yes that leaves for my final complaint. There should be a "camping mode" for the Defender. Every time you open the door it wakes up the car and by the end of the day you get the batter is low warning light on the dash. Absolutely annoying!
As much as I love the looks of the new Defender I will give the edge to looks for the LR3/4. All around for on road/off road there is nothing like the new Defender.